上周從中科院大連化物所傳出消息：國家“863”專項子課題——新型海洋生物農藥及植物促生(sheng)長劑(ji)產業化關鍵技(ji)術研究在該所通(tong)過(guo)科技(ji)部組織的驗收，這(zhe)標志(zhi)著我國新(xin)型海洋生(sheng)物農藥研發取得(de)重大突破。
課題組(zu)開發(fa)出海洋寡(gua)(gua)糖(tang)生物(wu)(wu)農(nong)(nong)(nong)藥、肥料(liao)及飼料(liao)添加(jia)劑規模化(hua)(hua)生產關鍵技術，獲得生物(wu)(wu)農(nong)(nong)(nong)藥正(zheng)(zheng)式登記證(zheng)、肥料(liao)登記證(zheng)、寡(gua)(gua)糖(tang)預混料(liao)生產許可證(zheng)各1個(ge)，申請(qing)國家發(fa)明專(zhuan)(zhuan)利17項。由海南正(zheng)(zheng)業中(zhong)農(nong)(nong)(nong)高科股份(fen)有限公(gong)司依托該項目建設的寡(gua)(gua)糖(tang)生物(wu)(wu)農(nong)(nong)(nong)藥高技術產業化(hua)(hua)示范(fan)工(gong)程今年已被列入國家綠色農(nong)(nong)(nong)用生物(wu)(wu)產品高技術產業化(hua)(hua)專(zhuan)(zhuan)項。
2007年(nian)，新型海(hai)(hai)(hai)洋(yang)生(sheng)物制品(pin)(pin)(pin)研(yan)究(jiu)(jiu)開發課題就被列為“十一五”國家“863”計劃(hua)海(hai)(hai)(hai)洋(yang)技術(shu)領域重點項目，中(zhong)科院大連化物所、中(zhong)國農科院飼料(liao)(liao)所、中(zhong)科院海(hai)(hai)(hai)洋(yang)所、西北大學等5家單位聯合承擔了(le)(le)該項目的(de)(de)子課題——新型海(hai)(hai)(hai)洋(yang)生(sheng)物農藥及(ji)植物促生(sheng)長劑產(chan)(chan)業化關鍵技術(shu)研(yan)究(jiu)(jiu)。課題組以海(hai)(hai)(hai)洋(yang)多糖(tang)(tang)為原料(liao)(liao)，通過研(yan)發高效(xiao)制備海(hai)(hai)(hai)藻(zao)(zao)酸(suan)寡糖(tang)(tang)、高活性殼(ke)寡糖(tang)(tang)其衍生(sheng)物的(de)(de)生(sheng)產(chan)(chan)工藝，形成了(le)(le)海(hai)(hai)(hai)藻(zao)(zao)酸(suan)寡糖(tang)(tang)、卡拉(la)膠寡糖(tang)(tang)及(ji)殼(ke)寡糖(tang)(tang)的(de)(de)分離(li)、純(chun)化及(ji)產(chan)(chan)品(pin)(pin)(pin)檢測(ce)技術(shu)，獲得(de)分離(li)純(chun)化海(hai)(hai)(hai)洋(yang)寡糖(tang)(tang)標準物11種(zhong)；初步建(jian)立了(le)(le)海(hai)(hai)(hai)洋(yang)寡糖(tang)(tang)誘抗劑及(ji)植物促生(sheng)長劑的(de)(de)高通量(liang)快速篩選技術(shu)平臺；研(yan)制出4種(zhong)新型海(hai)(hai)(hai)洋(yang)寡糖(tang)(tang)生(sheng)物農藥及(ji)植物促生(sheng)長劑產(chan)(chan)品(pin)(pin)(pin)，并對其進行(xing)了(le)(le)生(sheng)物安全性、穩(wen)定性、藥效(xiao)評價和應(ying)用技術(shu)等研(yan)究(jiu)(jiu)，建(jian)立了(le)(le)產(chan)(chan)品(pin)(pin)(pin)質量(liang)標準體(ti)系，取(qu)得(de)了(le)(le)創新性成果(guo)。
殼(ke)寡(gua)糖(tang)(tang)是以殼(ke)聚糖(tang)(tang)為(wei)原料，采用(yong)現代生(sheng)(sheng)(sheng)(sheng)(sheng)物(wu)(wu)(wu)化工新技(ji)(ji)術研制成(cheng)的具有(you)調(diao)控植物(wu)(wu)(wu)生(sheng)(sheng)(sheng)(sheng)(sheng)長、防治植物(wu)(wu)(wu)病害(hai)等功能的寡(gua)糖(tang)(tang)原料產品，是新一(yi)代海洋生(sheng)(sheng)(sheng)(sheng)(sheng)物(wu)(wu)(wu)農(nong)(nong)藥(yao)，無毒害(hai)、不污染環境，兼有(you)藥(yao)效和(he)(he)肥效雙重生(sheng)(sheng)(sheng)(sheng)(sheng)物(wu)(wu)(wu)調(diao)節功能。在課(ke)題實施過(guo)程中(zhong)(zhong)，課(ke)題組(zu)建(jian)立了(le)(le)中(zhong)(zhong)試工藝及(ji)質量控制標準(zhun)，形成(cheng)了(le)(le)一(yi)條成(cheng)熟、可(ke)行、易于(yu)放大、具有(you)我(wo)國(guo)自主(zhu)知(zhi)識產權(quan)的新技(ji)(ji)術和(he)(he)生(sheng)(sheng)(sheng)(sheng)(sheng)產工藝。2003年，課(ke)題組(zu)與大連(lian)凱飛(fei)化學股份有(you)限公(gong)司聯手，實現了(le)(le)寡(gua)糖(tang)(tang)生(sheng)(sheng)(sheng)(sheng)(sheng)物(wu)(wu)(wu)農(nong)(nong)藥(yao)產品的產業(ye)化；2009年，海南正業(ye)中(zhong)(zhong)農(nong)(nong)高科股份有(you)限公(gong)司建(jian)成(cheng)了(le)(le)1000噸/年規模(mo)的寡(gua)糖(tang)(tang)生(sheng)(sheng)(sheng)(sheng)(sheng)物(wu)(wu)(wu)農(nong)(nong)藥(yao)母藥(yao)生(sheng)(sheng)(sheng)(sheng)(sheng)產線和(he)(he)4000噸/年的寡(gua)糖(tang)(tang)生(sheng)(sheng)(sheng)(sheng)(sheng)物(wu)(wu)(wu)農(nong)(nong)藥(yao)制劑生(sheng)(sheng)(sheng)(sheng)(sheng)產線。
